I watched this last night, and I kept thinking, "Didn't I read the book?" But I guess not. Just one of those creative coincidences, maybe.
The house of the title is a living entity that eats kids, cops, and dogs. Naturally nobody believes it, though DJ, the kid who lives across the street tries to tell them. Mr. Nebbercracker, who lives in the house, seems almost as evil as the house itself. And Halloween is coming.
You can probably take things from here, if your imagination is wild enough. I liked the animation, most of the jokes, and the house itself. The story could have used some work, I thought. Maybe if it had been more like that book I read. . . .