The novel opens with Dr. Impossible in prison, having failed for the 12th time to achieve world domination. He escapes to try again, knowing down deep in his heart that he'll fail. But he has to try because he suffers from malign hypercognition disorder. Or because he's the new Sysiphus. I report, you decide.
Meanwhile CoreFire, the world's foremost superhero is missing and presumed dead, so the New Champions are formed to try to recapture Dr. Impossible, whom they suspect is responsible.
Villians, for some reason, are more fun to read about than heroes, and Dr. Impossible is a lot of fun. The chapters from Fatale's point of view are less successful, at least for me, but they're still okay. There are a number of twists, some of which you'll see coming, I'm sure, but I got a lot of laughs from Soon I Will Be Invincible. I don't know what comics fans think of it, but I'm sure they got more of the in-jokes than I did. You should check it out and see what you think.